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1

Simplified NaCl Based 68 Ga Concentration and Labeling Procedure for Rapid Synthesis of 68 Ga Radiopharmaceuticals in High Radiochemical Purity

Mueller, Dirk, Klette, Ingo, Baum, Richard P., Gottschaldt, M., Schultz, Michael K., Breeman, Wouter A. P.

Journal:

Bioconjugate Chemistry

Year:

2012

Language:

english

File:

PDF, 1.28 MB

english, 2012

2

Comparison of three radiolabelled peptide analogues for CCK-2 receptor scintigraphy in medullary thyroid carcinoma

Alida C. Fröberg, Marion de Jong, Berthold A. Nock, Wout A. P. Breeman, Jack L. Erion, Theodosia Maina, Marion Verdijsseldonck, Wouter W. de Herder, Aad van der Lugt, Peter P. M. Kooij, Eric P. Krenni

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2009

Language:

english

File:

PDF, 397 KB

english, 2009

3

Reduction of skeletal accumulation of radioactivity by co-injection of DTPA in [90Y-DOTA0,Tyr3]octreotide solutions containing free 90Y3+

Wouter A.P. Breeman, Maarten Th.M. De Jong, Erik De Blois, Bert F. Bernard, Marion De Jong, Eric P. Krenning

Journal:

Nuclear Medicine and Biology

Year:

2004

Language:

english

File:

PDF, 126 KB

english, 2004

4

The untapped potential of Gallium 68-PET: The next wave of 68Ga-agents

Smith, Daniel L., Breeman, Wouter A.P., Sims-Mourtada, Jennifer

Journal:

Applied Radiation and Isotopes

Year:

2013

Language:

english

File:

PDF, 1.45 MB

english, 2013

5

Optimizing labelling conditions of213Bi-DOTATATE for preclinical applications of peptide receptor targeted alpha therapy

Chan, Ho Sze, de Blois, Erik, Konijnenberg, Mark W., Morgenstern, Alfred, Bruchertseifer, Frank, Norenberg, Jeffrey P., Verzijlbergen, Fred J., de Jong, Marion, Breeman, Wouter A. P.

Journal:

EJNMMI Radiopharmacy and Chemistry

Year:

2017

Language:

english

File:

PDF, 1.07 MB

english, 2017

6

Lanthanide(III) Complexes of Bis(phosphonate) Monoamide Analogues of DOTA: Bone-Seeking Agents for Imaging and Therapy

Vitha, Tomáš, Kubíček, Vojtěch, Hermann, Petr, Elst, Luce Vander, Muller, Robert N., Kolar, Zvonimir I., Wolterbeek, Hubert T., Breeman, Wouter A.P., Lukeš, Ivan, Peters, Joop A.

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 181 KB

english, 2008

7

Optimising conditions for radiolabelling of DOTA-peptides with90Y,111In and177Lu at high specific activities

Breeman, Wouter A. P., Jong, Marion, Visser, Theo J., Erion, Jack L., Krenning, Eric P.

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2003

Language:

english

File:

PDF, 168 KB

english, 2003

8

Scaled-up radiolabelling of DOTATATE with 68Ga eluted from a SnO2-based 68Ge/68Ga generator

Daniel D. Rossouw, Wouter A.P. Breeman

Journal:

Applied Radiation and Isotopes

Year:

2012

Language:

english

File:

PDF, 179 KB

english, 2012

9

Overview of Development and Formulation of 177 Lu-DOTA-TATE for PRRT

A.P. Breeman, Wouter, Sze Chan, Ho, M.S. de Zanger, Rory, K. Konijnenberg, Mark, de Blois, Erik

Journal:

Current Radiopharmaceuticals

Year:

2015

Language:

english

File:

PDF, 524 KB

english, 2015

10

Influence of tumour size on the efficacy of targeted alpha therapy with 213Bi-[DOTA0,Tyr3]-octreotate

Chan, Ho Sze, Konijnenberg, Mark W., de Blois, Erik, Koelewijn, Stuart, Baum, Richard P., Morgenstern, Alfred, Bruchertseifer, Frank, Breeman, Wouter A., de Jong, Marion

Journal:

EJNMMI Research

Year:

2016

Language:

english

File:

PDF, 1.39 MB

english, 2016

11

Radiochemical and analytical aspects of inter-institutional quality control measurements on radiopharmaceuticals

de Blois, Erik, de Zanger, Rory M. S., Chan, Ho Sze, Konijnenberg, Mark, Breeman, Wouter A. P.

Journal:

EJNMMI Radiopharmacy and Chemistry

Year:

2019

File:

PDF, 1.41 MB

2019

12

Phase I study of peptide receptor radionuclide therapy with [111In-DTPA0]octreotide: The rotterdam experience

Roelf Valkema, Marion de Jong, Willem H. Bakker, Wout A.P. Breeman, Peter P.M. Kooij, Pieternella J. Lugtenburg, Frank H. de Jong, Arjan Christiansen, Boen L.R. Kam, Wouter W. de Herder, Mats Stridsbe

Journal:

Seminars in Nuclear Medicine

Year:

2002

Language:

english

File:

PDF, 2.59 MB

english, 2002

13

Five Stabilized 111 In-Labeled Neurotensin Analogs in Nude Mice Bearing HT29 Tumors

Janssen, Paul J.J.M., Visser, Moniaue de, Verwijnen, Suzanne M., Bernard, Bert F., Srinivasan, Ananth, Erion, Jack L., Breeman, Wouter A.P., Vulto, Arnold G., Krenning, Eric P., Jong, Marion de

Journal:

Cancer Biotherapy & Radiopharmaceuticals

Year:

2007

Language:

english

File:

PDF, 174 KB

english, 2007

14

Maintaining radiochemical purity of [177Lu]Lu-DOTA-PSMA-617 for PRRT by reducing radiolysis

de Zanger, Rory M. S., Chan, Ho Sze, Breeman, Wouter A. P., de Blois, Erik

Journal:

Journal of Radioanalytical and Nuclear Chemistry

Year:

2019

Language:

english

File:

PDF, 1.08 MB

english, 2019

15

Semi-automated system for concentrating 68 Ga-eluate to obtain high molar and volume concentration of 68 Ga-Radiopharmaca for preclinical applications

de Blois, Erik, de Zanger, Rory M.S., Oehlke, Elisabeth, Chan, Ho Sze, Breeman, Wouter A.P.

Journal:

Nuclear Medicine and Biology

Year:

2018

Language:

english

File:

PDF, 1004 KB

english, 2018

16

Optimised labeling, preclinical and initial clinical aspects of CCK-2 receptor-targeting with 3 radiolabeled peptides

Wouter A.P. Breeman, A.C. Fröberg, E. de Blois, A. van Gameren, M. Melis, M. de Jong, T. Maina, B.A. Nock, J.L. Erion, H.R. Mäcke, E.P. Krenning

Journal:

Nuclear Medicine and Biology

Year:

2008

Language:

english

File:

PDF, 1020 KB

english, 2008

17

The addition of DTPA to [177Lu-DOTA0,Tyr3]octreotate prior to administration reduces rat skeleton uptake of radioactivity

Breeman, Wouter A., van der Wansem, Katy, Bernard, Bert F., van Gameren, Arthur, Erion, Jack L., Visser, Theo J., Krenning, Eric P., de Jong, M.

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2003

Language:

english

File:

PDF, 219 KB

english, 2003

18

Radiolabeling of DOTA-like conjugated peptides with generator-produced 68Ga and using NaCl-based cationic elution method

Mueller, Dirk, Breeman, Wouter A P, Klette, Ingo, Gottschaldt, Michael, Odparlik, Andreas, Baehre, Manfred, Tworowska, Izabela, Schultz, Michael K

Journal:

Nature Protocols

Year:

2016

Language:

english

File:

PDF, 1.47 MB

english, 2016

19

Determination of peptide content and purity of DOTA-peptides by metal ion titration and UPLC: an alternative method to monitor quality of DOTA-peptides

Breeman, Wouter A. P., Chan, Ho Sze, de Blois, Erik

Journal:

Journal of Radioanalytical and Nuclear Chemistry

Year:

2014

Language:

english

File:

PDF, 563 KB

english, 2014

20

Radiochemical and analytical aspects of inter-institutional quality control measurements on radiopharmaceuticals

de Blois, Erik, de Zanger, Rory M. S., Chan, Ho Sze, Konijnenberg, Mark, Breeman, Wouter A. P.

Journal:

EJNMMI Radiopharmacy and Chemistry

Year:

2019

Language:

english

File:

PDF, 1.41 MB

english, 2019

21

Characteristics of SnO2-based 68Ge/68Ga generator and aspects of radiolabelling DOTA-peptides

Erik de Blois, Ho Sze Chan, Clive Naidoo, Deidre Prince, Eric P. Krenning, Wouter A.P. Breeman

Journal:

Applied Radiation and Isotopes

Year:

2011

Language:

english

File:

PDF, 478 KB

english, 2011

22

The detection of virally induced tumors by131I- and125I-labeled syngeneic monoclonal antibodies

Derk Berends, Joseph L. M. Gaalen, Els H. Rhijnsburger, Nico J. Both, Wouter Breeman, Willem H. Bakker, Peter Kooy

Journal:

Cancer Immunology, Immunotherapy

Year:

1988

Language:

english

File:

PDF, 1.49 MB

english, 1988

23

Correction to Simplified NaCl Based 68 Ga Concentration and Labeling Procedure for Rapid Synthesis of 68 Ga Radiopharmaceuticals in High Radiochemical Purity

Mueller, Dirk, Klette, Ingo, Baum, Richard P., Gottschaldt, M., Schultz, Michael K., Breeman, Wouter A. P.

Journal:

Bioconjugate Chemistry

Year:

2013

Language:

english

File:

PDF, 117 KB

english, 2013

24

Reduction of68Ge activity containing liquid waste from68Ga PET chemistry in nuclear medicine and radiopharmacy by solidification

Erik de Blois, Ho Sze Chan, Kamalika Roy, Eric P. Krenning, Wouter A. P. Breeman

Journal:

Journal of Radioanalytical and Nuclear Chemistry

Year:

2011

Language:

english

File:

PDF, 391 KB

english, 2011

25

Speciation of no-carrier-added68Ga prior to its labeling for PET imaging

Kamalika Sen, Wouter A. P. Breeman, H. Th. Wolterbeek

Journal:

Journal of Radioanalytical and Nuclear Chemistry

Year:

2012

Language:

english

File:

PDF, 247 KB

english, 2012

26

Anti-proliferative effect of radiolabelled octreotide in a metastases model in rat liver

Gerrit D. Slooter, Wouter A.P. Breeman, Richard L. Marquet, Eric P. Krenning, Casper H.J. van Eijck

Journal:

International Journal of Cancer

Year:

1999

Language:

english

File:

PDF, 186 KB

english, 1999

27

Anti-tumor effect and increased survival after treatment with [177Lu-DOTA0,Tyr3]octreotate in a rat liver micrometastases model

Wouter A.P. Breeman, Amir Mearadji, Astrid Capello, Bert F. Bernard, Casper H.J. van Eijck, Eric P. Krenning, Marion de Jong

Journal:

International Journal of Cancer

Year:

2003

Language:

english

File:

PDF, 82 KB

english, 2003

28

Improved safety and efficacy of213Bi-DOTATATE-targeted alpha therapy of somatostatin receptor-expressing neuroendocrine tumors in mice pre-treated withl-lysine

Chan, Ho Sze, Konijnenberg, Mark W., Daniels, Tamara, Nysus, Monique, Makvandi, Mehran, de Blois, Erik, Breeman, Wouter A., Atcher, Robert W., de Jong, Marion, Norenberg, Jeffrey P.

Journal:

EJNMMI Research

Year:

2016

Language:

english

File:

PDF, 1.64 MB

english, 2016

29

Aspects on radiolabeling of 177Lu-DOTA-TATE: After C18 purification re-addition of ascorbic acid is required to maintain radiochemical purity

Maus, Stephan, Blois, Erik De, Ament, Stephan J., Schreckenberger, Mathias, Breeman, Wouter A. P.

Journal:

International Journal of Diagnostic Imaging

Year:

2014

Language:

english

File:

PDF, 140 KB

english, 2014

30

2-Methoxyisobutylisonitrile Probe during Parathyroid Surgery: Tool or Gadget?

H. Jaap Bonjer, Hajo A. Bruining, Huib A.P. Pols, Wouter W. de Herder, Charles A.G. Proye, Bruno M.L. Carnaille, Robert S.A. Mohammedamin, Ewout W. Steyerberg, Wout A.P. Breeman, Erik P. Krenning

Journal:

World Journal of Surgery

Year:

1998

Language:

english

File:

PDF, 133 KB

english, 1998

31

68Ga-labeled DOTA-Peptides and 68Ga-labeled Radiopharmaceuticals for Positron Emission Tomography: Current Status of Research, Clinical Applications, and Future Perspectives

Wouter A.P. Breeman, Erik de Blois, Ho Sze Chan, Mark Konijnenberg, Dik J. Kwekkeboom, Eric P. Krenning

Journal:

Seminars in Nuclear Medicine

Year:

2011

Language:

english

File:

PDF, 636 KB

english, 2011

32

The68Ge/68Ga generator has high potential, but when can we use68Ga-labelled tracers in clinical routine?

Wouter A. P. Breeman, Alfons M. Verbruggen

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2007

Language:

english

File:

PDF, 89 KB

english, 2007

33

Reversed phase free ion selective radiotracer extraction (RP-FISRE): A new tool to assess the dynamic stabilities of metal (-organic) complexes, for complex half-lives spanning six orders of magnitude

van der Meer, Astrid, Breeman, Wouter A.P., Wolterbeek, Bert

Journal:

Applied Radiation and Isotopes

Year:

2013

Language:

english

File:

PDF, 434 KB

english, 2013

34

THE CHOLERA.

van der Meer, Astrid, Breeman, Wouter A.P., Wolterbeek, Bert

Journal:

Year:

1854

Language:

english

File:

PDF, 202 KB

english, 1854

35

Application of single-vial ready-for-use formulation of 111In- or 177Lu-labelled somatostatin analogs

de Blois, Erik, Chan, Ho Sze, de Zanger, Rory, Konijnenberg, Mark, Breeman, Wouter A.P.

Journal:

Applied Radiation and Isotopes

Year:

2014

Language:

english

File:

PDF, 484 KB

english, 2014

36

Clean Intermittent Catheterisation

van der Meer, Astrid, Breeman, Wouter A.P., Wolterbeek, Bert

Journal:

Year:

1979

Language:

english

File:

PDF, 293 KB

english, 1979

37

Radiolabelling DOTA-peptides with68Ga

Wouter A. P. Breeman, Marion de Jong, Erik de Blois, Bert F. Bernard, Mark Konijnenberg, Eric P. Krenning

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2005

Language:

english

File:

PDF, 262 KB

english, 2005

38

A new automated NaCl based robust method for routine production of gallium-68 labeled peptides

Schultz, Michael K., Mueller, Dirk, Baum, Richard P., Leonard Watkins, G., Breeman, Wouter A.P.

Journal:

Applied Radiation and Isotopes

Year:

2013

Language:

english

File:

PDF, 1.75 MB

english, 2013

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